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KMID : 0378019790220040027
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New Medical Journal
1979 Volume.22 No. 4 p.27 ~ p.29
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A Case of Tilidine Addiction
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Abstract
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In this case report of Tilidine addiction, the authors suggested that Tilidine was definitely addict-forming drug very similar to Morphine by nature.
The case, 27 year old´ Caucasian American male, has taken 13,000 mg of Tilidine daily for 8 months. Gradual withdrawal of the drug was impossible because of his intolerance of withdrawal symptoms. Nalorphine test resulted in positive response during the initial maintenance medication of Tilidine. Typical withdrawal symptoms such as yawning, lacrimation, rhinorrhea, chilliness perspiration, sneezing, uncontrollable insomnia could be evaluated 4 hours after withdrawal and goose flesh, tremor and muscle cramp of the face, extremities and abdomen, anorexia, increased blood pressure and pulse, urinary incontinence, diarrhea, vomiting and brownish discoloration of both eye lids and emotional excitement were noticed 24 hours after withdrawal. The symptoms subsided on the 7th day of abstinence.
The authors gave warning to possible increase of Tilidine addiction in the future, because the drug is easily accessible in the market in this country.
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